In an effort to keep all of our patients updated on the
latest developments in healthcare, we at LernerCohen have available the new
Herpes Zoster vaccine, Zostavax, for our patients. The following is a brief
summary of the product details to help our patients decide if the vaccine is
appropriate for them. As always please feel free to discuss any issues with
your
Physician.
On May 26,2006, the U.S. Food and Drug Administration
(FDA) has approved the very first vaccine for the prevention of Herpes Zoster
(Shingles) in people 60 years of age and older.
Herpes Zoster is a ubiquitous viral infection that
usually affects young children in a disseminated fashion causing a febrile
illness with a diffuse blistering eruption known as “chickenpox”. This is
usually a mild, self
limited illness with no long term sequelae. Once the virus affects its host, it
then lays dormant for many years, often forever. Unfortunately, for reasons
that are not known, reactivation of this virus can occur, often in older
individuals. Upon reactivation, the virus usually manifests as a blistering
very painful eruption in a very localized area. The incidence and severity of
Shingles, as well the
frequency and severity of its complications, increase with age. Long term nerve
pain, known as post herpetic neuralgia, is perhaps the most dreaded complication
of Shingles.
Zostavax vaccine has been studied in 38,000 patients for
an average of 3 years. It decreased the incidence of Shingles by 51%, and in
those individuals who did develop Shingles, it decreased the development of post
herpetic neuralgia by 39%. Injection site reaction consisting mostly of pain
and localized swelling were the primary side effects of the vaccination. There
have thus far been no significant vaccine related serious side
effects.
Zostavax is a live attenuated vaccine, meaning that the
vaccine has been weakened so as not to cause infection yet to still elicit an
immune response. Because it is a live vaccine it should NOT be given to people
who are immunocompromised. Leukemia, lymphoma, current chemotherapy, HIV and
high dose steroid therapy treatment are all contraindications to treatment.
People who have had shingles and therefore have high antibody levels are also
not candidates for the vaccine.
Zostavax should be considered for all appropriate people
over age 60. We will be offering this in our office setting as well as at our
upcoming health fair in the Fall. We hope this answers any questions you may
have. Please call your Physician for further discussion in this
regard.